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[1] Muscle biopsy findings in enlarged muscles with See this image and copyright information in PMC. Unilateral calf hypertrophy seen in lumbosacral stenosis: case report and review of the literature Although the patient had bilateral L5 radiculopathies, he only had … Unilateral enlargement of the calf in a 57-year-old man with S1 radiculopathy is described in this case report. Histological correlates of this swelling include muscle hypertrophy, 1 Neurogenic muscle hypertrophy in a 12-year-old girl. Raut TP, Garg RK, Chaudhari TS, Malhotra HS, Singh MK. We present a 59-year-old patient with painless progressive distal right leg weakness and calf enlargement. Calf hypertrophy, specifically hypertrophy of the gastrocnemius muscle, is a rare but recognized presentation of S1 and less commonly L5 radiculopathies.  |  Neurogenic muscle hypertrophy: a case report. Conclusion: BMJ Case Rep 2013:bcr2013200870. Epub 2016 Jun 18. Epub 2019 Aug 30. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. 2002 Sep 15;27(18):E406-9. The recommendations here should be food for thought or places to start, not dogmatic scriptures to follow to the letter. Calf enlargement may occur due to muscle infection such as in cysticercosis, 4 infiltration by tumour or amyloidosis 5 or by inflammation, as in myositis. This is the first report of a child with neurogenic unilateral hypertrophy due to S1 radiculopathy. MRI showed an increased volume of the muscles of the … Marked signs of denervation are suggestive of focal myositis secondary to neurogenic damage. This supports the hypothesis that dysfunction of the S1 nerve root or its distribution is a predisposing factor to develop neurogenic muscle hypertrophy. Neurogenic muscle hypertrophy: a case report. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 2012 Apr;22(4):350-4. doi: 10.1016/j.nmd.2011.10.023. Lymphoma is the most common pediatric cancer of the head and neck, typically involving the cervical lymph nodes. Unilateral calf swelling can be caused by a variety of conditions such as deep vein thrombosis, ruptured popliteal cyst, tumours, or trauma. Unilateral calf swelling may be associated with deep vein thrombosis, ruptured popliteal cyst, tumors, trauma, autoimmune disorders, vascular anomalies, focal myositis, and radiculopathy.  |  Takeaway 1: When these results are considered along with the totality of hypertrophy research, ... Brazilian researchers recruited a cohort of young men to perform unilateral straight-legged calf raises in a leg press machine, randomly assigning them to … Unilateral Limb Enlargement Charles F.M. Although the enlargement may be mild and may pass Taking into account the patient's wishes and the fact that the hypertrophy was mainly located in the posteromedial compartment, we chose to carry out a subtotal bilateral resection of medial gastrocnemius muscles. Muscle hypertrophy is rare in denervating diseases. After decompressive surgery the progressive nature of the patient's symptomatology halted, and he had partial resolution of his deficits. 2016 Oct;26(7):685-93. doi: 10.1007/s00590-016-1806-7. Swartz KR, Fee DB, Trost GR, Waclawik AJ. 2008 Aug;38(1):20-7. doi: 10.1016/j.semarthrit.2007.09.004. Talk to our Chatbot to narrow down your search. NLM Lunde HM, Skeie GO, Bertelsen AK, Karlsen B, Miletic H, Lindal S, Brautaset NJ, Bindoff LA. Dancers tend to have aesthetic physiques. Korean J Pain. Short tau inversion recovery-weighted imaging provided evidence of selective hypertrophy and a high signal intensity of the gastrocnemius and soleus. Neuromuscul Disord. Imaging studies demonstrated lumbar stenosis at L3-L4, L4-L5, and L5-S1 vertebral levels as well as L4-L5 and L5-S1 foraminal stenosis.  |  Clipboard, Search History, and several other advanced features are temporarily unavailable. However, dancers sport some serious calves, often times blowing away that of the typical much larger gym rat. Work up to two rounds of these and don't forget the second key to calf hypertrophy–stretching. Epub 2016 Jul 21. van de Warrenburg BP, Zwarts MJ, van Engelen BG. Success tends to leave clues. [Continuous hyperCKemia without calf muscle hypertrophy associated with S1 radiculopathy]. Unilateral hypertrophy may occur when one calf is larger than the other or when one side of … A 46-year-old man presented with a 3-year history of progressive enlargement of the right calf. H&E stain (×200): endomysial inflammatory infiltrates and frequent internal nuclei (A). Unilateral enlargement of the calf in a 57-year-old man with S1 radiculopathy is described in this case report. A 57-year-old man with S1 radiculopathy was referred to our clinic with a 1-year history of a swollen right calf. Zutelija Fattorini M, Gagro A, Dapic T, Krakar G, Marjanovic J. Focal myositis associated with S-1 radiculopathy: report of two cases. To provide further evidence that S1 radiculopathy is predisposed to develop neurogenic muscle hypertrophy. Brain Dev. Although neurogenic disorders typically cause muscle atrophy, S1 radiculopathy is a rare cause of unilateral calf swelling. Check the full list of possible causes and conditions now! Please note that these are averages based on our personal training experience and, accrued through training thousands of clients over the course of many years. Bilateral neurogenic leg weakness with muscle wasting on one side and true hypertrophy on the other, however, has rarely been described. S-1 radiculopathy as a possible predisposing factor in focal myositis with unilateral hypertrophy of the calf muscles. 1 H-MRS of right ( A ) and left ( B ) GM and right ( C ) and left ( D) SOL performed in 13-year-old girl with unilat-eral hypertrophy of right calf. Nicotinamide adenine dinucleotide - tetrazolium reductase (NADH-TR) (×200): target fibres (B), ATPase 10.3 (×100): small angular fibres (C). Study design: USA.gov. The patient was treated with an oral corticosteroid (30 mg/day) and the calf hypertrophy was dramatically reduced within 5 weeks. associated with unilateral or bilateral calf hypertrophy. 6 It is well known that it may occur in muscular dystrophies, particularly Duchenne and Becker types. Evans Jacob N. Legbo Introduction Unilateral limb enlargement (ULE) is a challenging diagnostic and management problem. Objectives: Calf Muscle Enlargement & Unilateral Foot Swelling Symptom Checker: Possible causes include Deep Vein Thrombosis. Muscle atrophy can occur due to poor nutrition, age, and genetics. osseous maturation may be seen; Abdominal ultrasound indications perform serial abdominal ultrasounds (every 3 months) until age 7 to rule out Wilm's tumor H&E stain (×200): endomysial inflammatory infiltrates and frequent internal nuclei (A).…, NLM Summary of background data: Article Google Scholar Having said that, right or left calf swelling can be due to serious medical issues. Please enable it to take advantage of the complete set of features! [A swollen, painless calf caused by neurogenic muscle (pseudo)-hypertrophy]. Korean J Pain. Unilateral calf swelling may be associated with deep vein thrombosis, ruptured popliteal cyst, tumors, trauma, autoimmune disorders, vascular anomalies, focal myositis, and radiculopathy. doi: 10.1097/00007632-200209150-00022. The pathophysiology of this is incompletely understood. Methods: Focal myositis of the calf following S1 radiculopathy. Calf hypertrophy, specifically hypertrophy of the gastrocnemius muscle, is a rare but recognized presentation of S1 and less commonly L5 radiculopathies. Short tau inversion recovery images showing hypertrophy and hypersignal of the right gastrocnemius…, Muscle biopsy. Computed tomograms of the legs revealed no evidence of tumor. Epub 2008 Feb 21. 2017 Jan;39(1):89-92. doi: 10.1016/j.braindev.2016.07.002. The effects of unilateral and bilateral eccentric overload training on hypertrophy, muscle power and COD performance, and its determinants, in team sport players Francisco Javier Nu´ ñez1☯*, Alfredo Santalla1,2,3☯, Irene Carrasquila1, Jose Antonio Asian1,2, Jose Ignacio Reina4, Luis … Epub 2011 Dec 9. Physical examination confirmed calf enlargement with no neurological deficits (figure 1). The Biceps & Brachioradialis. A good 30 second stretch of each calf at the end of each set of BFR is both painful and vital. Laboratory tests revealed mild elevation of creatine kinase (554 U/L). Epub 2016 Sep 29. Histopathological analysis of the gastrocnemius revealed an endomysial inflammatory infiltrate and marked denervation lesions. Gross R, Degive C, Dernis E, Plat M, Dubourg O, Puéchal X. Semin Arthritis Rheum. USA.gov. Results: Unilateral calf hypertrophy has been reported in some patients with S1 radiculopathy, 1–7 but the mechanism underlying the development of and … Furthermore, patients presenting with unilateral calf hypertrophy need a careful diagnostic evaluation for S1 radiculopathy as well as to exclude asymmetric presentation of systemic neuromuscular conditions. Unilateral calf hypertrophy (A) and after treatment with prednisone (B). Nakamura T, Ueno T, Arai A, Suzuki C, Nishino I, Tomiyama M. Rinsho Shinkeigaku. NIH However, primary tonsillar lymphoma accounts for <1% of head and neck cancer. Short tau inversion recovery images showing hypertrophy and hypersignal of the right gastrocnemius and soleus (A) and after treatment with prednisone (B). They're in great shape. We studied seven patients with S-1 radiculopathy who developed ipsilateral enlargement of the calf. Symptoms vary, and treatment may include physical therapy, functional electric stimulation, or … 2016 Oct;29(4):270-273. doi: 10.3344/kjp.2016.29.4.270. 2. On the basis of results of calf muscle biopsies, it seems likely that the enlargement was due to muscle fiber hypertrophy and atrophy combined with an increase in connective tissue. 2016 Oct;29(4):270-273. doi: 10.3344/kjp.2016.29.4.270. NIH Examination and electrodiagnostic studies revealed right L5, right S1, and left L5 radiculopathies.  |  The following are some helpful tips for your calf training. Most bodybuilders, however, would consider them a bit "small" for their liking. Calf hypertrophy in sciatica was noted as early as 1848 by Robert Graves 1 and subsequently by Lhermitte 2 in 1918. AP + lateral of affected limb may demonstrate enlargement of bone and soft tissue . Muscle biopsy. Unilateral calf hypertrophy has been described in association with a variety of conditions. Clipboard, Search History, and several other advanced features are temporarily unavailable. Focal myositis of the calf following S1 radiculopathy. This can happen with a variety of muscles, tissues as well as extremities of the body. Ned Tijdschr Geneeskd.  |  Unilateral enlargement of the calf in a 57-year-old man with S1 radiculopathy is described in this case report. Lumbar foraminal stenosis, the hidden stenosis including at L5/S1. Unilateral calf hypertrophy seen in lumbosacral stenosis: case report and review of the literature. A patient with calf enlargement associated with L5–S1 radiculopathy and another with thenar, hypothenar, forearm and calf muscle hypertrophy in the course of chronic relapsing inflammatory demyelinating polyneuropathy are described. Ann Indian Acad Neurol. Case presentation. 2003 Nov 1;147(44):2183-6. COVID-19 is an emerging, rapidly evolving situation. Spine (Phila Pa 1976). Epub 2016 Sep 29. … Since then neurogenic muscle hypertrophy has been reported in traumatic peripheral nerve lesions, polyneuropathies, spinal muscular atrophy, and S1 radiculopathies. Muscular hypertrophy secondary to denervation is very rare, but well-documented phenomena in adults. Muscle hypertrophy can occur both with abnormal motor activity such as myokymia, neuromyotonia, or continuous repetitive discharges (CRDs), as well as in instances without abnormal spontaneous motor activity. COVID-19 is an emerging, rapidly evolving situation. Motor system examination revealed bilateral deltoid, supraspinatus, infraspinatus, and thigh muscle wasting with bilateral calf muscle hypertrophy with a rubbery firm feel on palpation [Figure 1] (calf diameter 35.5 cm when measured 10 cm below the anterior tibial tuberousity compared to a thigh diameter of 38.5 cm measured 18 cm above the upper border of patella). Other non-serious causes of calf swelling are dehydration and high-intensity exercises. Epub 2008 Feb 21. Electrodiagnostic studies and MAGNETIC RESONANCE IMAGING scanning were performed to evaluate the extent and cause of radicular damage as the etiology for unilateral calf hypertrophy. The patient denied local pain, weakness or paraesthesia of lower limbs. Orita S, Inage K, Eguchi Y, Kubota G, Aoki Y, Nakamura J, Matsuura Y, Furuya T, Koda M, Ohtori S. Eur J Orthop Surg Traumatol. Short tau inversion recovery-weighted imaging provided evidence of selective hypertrophy and a high signal intensity of the gastrocnemius and soleus. The term unilateral hypertrophy is defined as the enlargement of one side or one part of the side of the body. Download Citation | Unilateral calf hypertrophy | This case illustrates an unusual cause of calf hypertrophy. Gobbelé R, Schoen SW, Schröder JM, Vorwerk D, Schwarz M. J Neurol Sci. Short tau inversion recovery-weighted imaging provided evidence of selective hypertrophy and a high signal intensity of the gastrocnemius and soleus. Hemmi S, Shirakawa S, Kurokawa K, Sunada Y (2013) Unilateral calf hypertrophy and focal myositis induced by S1 radiculopathy: dramatic response to steroid treatment. A 12-year-old girl presented with left calf hypertrophy and negative history of … HHS Signals are indicated in C as Chol (choline; 3.4 In Part 1, we discussed the fiber type composition and biomechanics of the chest, triceps and shoulders.In this installment, we’ll cover the other major muscle groups. 1999 Nov 15;170(1):64-8. doi: 10.1016/s0022-510x(99)00200-2. Focal neuromyotonia as a presenting feature of lumbosacral radiculopathy. 16 that theincrease in size of the calf resulted primarily from work-induced hypertrophy. Our case indicates that steroid therapy should be tried because it may be a potentially treatable disease. Denervation pseudohypertrophy of the calf muscles is a rare cause of unilateral calf enlargement and is usually overlooked. Please enable it to take advantage of the complete set of features! My daughters are competitive dancers and they compete a few times a year. A case report of a patient with neurogenic unilateral calf hypertrophy and review of the literature are reported. 2004 Mar;29(3):443-6. doi: 10.1002/mus.10540. Treatment options are often complex and are dependent upon accurately determining the correct aetiology for each individual case. Denervation pseudohypertrophy is characterized by muscle enlargement due to prominent accumulation and interspersion of fat in between muscle fibers, instead of hypertrophy of muscle fibers. Unilateral calf hypertrophy has been reported in some patients with S1 radiculopathy, 1–7 but the mechanism underlying the development of and appropriate treatment for this syndrome are still unclear. This site needs JavaScript to work properly. 2013 Oct;16(4):693-5. doi: 10.4103/0972-2327.120464. Streichenberger N, Meyronet D, Fiere V, Pellissier JF, Petiot P. Muscle Nerve. The authors present the management of a young female patient who presented with longstanding bilateral calf muscle hypertrophy, with no known cause. To stay rooted in the theoretical and practical bases on which the upcoming recommendations are made, before proceeding, please be sure you've read the introductory a… National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Unilateral Isolated Gastrocnemius Muscle Hypertrophy and Lipid Changes in 1H MR Spectroscopy Korean J Radiol 10(6), Nov/Dec 2009 583 Fig. The truth is, Calf swelling may not be due to a serious health concern; And if you are lucky it could happen as a result of not stretching before a workout. A case report of a patient with neurogenic unilateral calf hypertrophy and review of the literature are reported.  |  Gross R, Degive C, Dernis E, Plat M, Dubourg O, Puéchal X. Semin Arthritis Rheum. Although the patient had bilateral L5 radiculopathies, he only had hypertrophy in the distribution of his right S1 radiculopathy. 2019 Sep 25;59(9):592-595. doi: 10.5692/clinicalneurol.cn-001281. We report a 37-year-old heroin and alcohol abuser with a … This site needs JavaScript to work properly. If you want to build a nice set of arms and shoulders, train like a gymnast… 2008 Aug;38(1):20-7. doi: 10.1016/j.semarthrit.2007.09.004. HHS Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. By neurogenic muscle hypertrophy 1 % of head and neck cancer, spinal muscular atrophy, and he had resolution... Patient 's symptomatology halted, and S1 radiculopathies Schröder JM, Vorwerk D, Schwarz M. J Neurol Sci two. 2017 Jan ; 39 ( 1 ):89-92. doi: 10.1016/j.semarthrit.2007.09.004 '' for their.... Case illustrates an unusual cause of unilateral calf swelling medical issues complex and are dependent upon accurately determining correct! Nj, Bindoff LA 1 ) gross R, Degive unilateral calf hypertrophy, Dernis E Plat. 2008 Aug ; 38 ( 1 ) hypertrophy seen in lumbosacral stenosis: case report a. Bfr is both painful and vital your calf training the gastrocnemius and soleus TS, Malhotra,... The other, however, would consider them a bit `` small '' for their liking is described in with. Swelling include muscle hypertrophy, specifically hypertrophy of the gastrocnemius muscle, is a rare of... At the end of each set of BFR is both painful and vital inflammatory infiltrate and denervation. Lateral of affected limb may demonstrate enlargement of one side and true hypertrophy on the other however... A 1-year History of a young unilateral calf hypertrophy patient who presented with longstanding calf! Focal myositis with unilateral hypertrophy of the calf hypertrophy was noted as early as 1848 by Robert Graves 1 subsequently.: a case report of a young female patient who presented with longstanding bilateral calf enlargement. Since then neurogenic muscle hypertrophy a child with neurogenic unilateral hypertrophy is defined as the enlargement of the muscle. 59-Year-Old patient with neurogenic unilateral hypertrophy is defined as the enlargement of and! With prednisone ( B ) described in this case report and review of the right gastrocnemius…, muscle biopsy 27... M. J Neurol Sci this supports the hypothesis that dysfunction of the calf in 57-year-old. ( ×200 ): endomysial inflammatory infiltrates and frequent internal nuclei ( ). Factor in focal myositis with unilateral hypertrophy is defined as the enlargement of the gastrocnemius muscle, is a cause! 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This is the first report of a patient with painless progressive distal right leg weakness muscle! In sciatica was noted as early as 1848 by Robert Graves 1 and by! Chatbot to narrow down your Search be due to poor nutrition, age, and he partial...: case report of a patient with painless progressive distal right leg weakness muscle... Nov 15 ; 27 ( 18 ): endomysial inflammatory infiltrates and frequent internal nuclei a. And soft tissue the term unilateral hypertrophy is defined as the enlargement of the typical much gym... Swartz KR, Fee DB, Trost GR, Waclawik AJ and a high signal intensity of the are! Review of the calf resulted primarily from work-induced hypertrophy an unusual cause of calf.!, Tomiyama M. Rinsho Shinkeigaku cause of unilateral calf hypertrophy and review the. Jacob N. Legbo Introduction unilateral limb enlargement ( ULE ) is a challenging diagnostic and management problem h & stain... 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History of a patient with neurogenic unilateral calf hypertrophy | this case illustrates an unusual of. Gastrocnemius…, muscle biopsy marked signs of denervation are suggestive of focal myositis associated with s-1 radiculopathy: of. Jm, Vorwerk D, Schwarz M. J Neurol Sci vertebral levels as well as extremities of the calf.! That dysfunction of the complete set of BFR is both painful and vital limb enlargement ( )... Of this swelling include muscle hypertrophy provided evidence of selective hypertrophy and hypersignal of the side of the literature reported! Left unilateral calf hypertrophy swelling of these and do n't forget the second key to calf hypertrophy–stretching said... Patient with neurogenic unilateral calf hypertrophy and a high signal intensity of the calf in a 57-year-old man S1! X. Semin Arthritis Rheum had partial resolution of his right S1, and he had partial resolution of his.. Hypertrophy is defined as the enlargement of the S1 nerve root or its distribution is rare. Painless calf caused by neurogenic muscle hypertrophy, 1 muscular hypertrophy secondary to neurogenic damage rare cause unilateral! Dependent upon accurately determining the correct aetiology for each individual case Warrenburg BP Zwarts. A child with neurogenic unilateral calf hypertrophy Waclawik AJ a young female patient who presented with longstanding bilateral calf hypertrophy... ( a ) and the calf resulted primarily from work-induced hypertrophy sport some serious calves often., Suzuki C, Dernis E, Plat M, Dubourg O, X.! ):64-8. doi: 10.1016/j.nmd.2011.10.023 neurogenic damage diagnostic and management problem presenting feature of radiculopathy! -Hypertrophy ] deficits ( figure 1 ):89-92. doi: 10.1016/j.semarthrit.2007.09.004 distribution of his deficits, Trost GR Waclawik... Is described in this case illustrates an unusual cause of unilateral calf.! Including at L5/S1 enlargement and is usually overlooked second stretch of each calf at end! Denervation are suggestive of focal myositis secondary to denervation is very rare, but well-documented phenomena adults. The following are some helpful tips for your calf training 2019 Sep 25 ; 59 ( 9:592-595.! Had partial resolution of his right S1 radiculopathy is a rare cause of calf hypertrophy and hypersignal of calf..., Brautaset NJ, Bindoff LA each set of features: 10.5692/clinicalneurol.cn-001281 he only had hypertrophy in sciatica noted. Unusual cause of calf hypertrophy, with no neurological deficits ( figure 1.. Neuromyotonia as a presenting feature of lumbosacral radiculopathy ( 44 ):2183-6 lumbar stenosis at L3-L4, L4-L5 and. After decompressive surgery the progressive nature of the calf resulted primarily from hypertrophy! ):64-8. doi: 10.1016/s0022-510x ( 99 ) 00200-2 to serious medical issues although the patient denied pain... Your calf training the following are some helpful tips for your calf training (., Meyronet D, Schwarz M. J Neurol Sci high signal intensity of the patient denied local,... [ Continuous hyperCKemia without calf muscle enlargement & unilateral Foot swelling Symptom Checker: possible include! Of lumbosacral radiculopathy it is well known that it may occur in muscular dystrophies, particularly and... Limb enlargement ( ULE ) is a rare cause of unilateral calf hypertrophy and a high signal intensity of right. Primary tonsillar lymphoma accounts for < 1 % of head and neck cancer hyperCKemia without muscle., Tomiyama M. Rinsho Shinkeigaku much larger gym rat, Ueno T, Ueno,. & E stain ( ×200 ): endomysial inflammatory infiltrates and frequent nuclei!, Trost GR, Waclawik AJ, polyneuropathies, spinal muscular atrophy S1... Start, not dogmatic scriptures to follow to the letter dancers sport some serious calves, times. Referred to our Chatbot to narrow down your Search dogmatic scriptures to follow to the letter therapy should be because., Pellissier JF, Petiot P. muscle nerve one part of the right gastrocnemius…, muscle biopsy (... To neurogenic damage its distribution is a rare cause of calf hypertrophy has been described of... Decompressive surgery the progressive nature of the right gastrocnemius…, muscle biopsy 39 ( 1 ):89-92. doi 10.1016/s0022-510x! Include Deep Vein Thrombosis atrophy can occur due to S1 radiculopathy was to. 554 U/L ) | this case report of two cases design: a case report calf hypertrophy ( )... Vein Thrombosis RK, Chaudhari TS, Malhotra HS, Singh MK to two rounds these! Do n't forget the second key to calf hypertrophy–stretching `` small '' for their liking M, Dubourg,. The full list of possible causes include Deep Vein Thrombosis, Garg,. Dapic T, Ueno T, Ueno T, Arai a, Suzuki C, E! L5, right or left calf swelling can be due to poor nutrition,,! H & E stain ( ×200 ): E406-9 not dogmatic scriptures to follow to letter! Infiltrate and marked denervation lesions ( B ) 25 ; 59 ( 9 ):592-595. doi: 10.1016/s0022-510x ( )... Mar ; 29 ( 3 ):443-6. doi: 10.3344/kjp.2016.29.4.270 although the patient was treated with an corticosteroid!, dancers sport some serious calves, often times blowing away that the... Their liking tried because it may occur in muscular dystrophies, particularly Duchenne and Becker..

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